Differences in social status in allostatic load in young adults in the United States

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SSM Population Health. Apr 2, 2021; 15: 100771. doi: 10.1016 / j.ssmph.2021.100771. eCollection 2021 Sep.

ABSTRACT

Allostatic load refers to the wear and tear of the body due to the repeated activation of the stress response and, therefore, can be an early subclinical indicator of future risk of disease and death. To date, few studies of allostatic load have focused on young adults, racial / ethnic comparisons that include Mexican Americans, or the interplay between race / ethnicity, gender, and level of education. ‘instruction. To fill these gaps, we used data on non-Hispanic black, non-Hispanic white, and Mexican respondents of Waves I (1994-1995) and IV (2007-2008) of the National Longitudinal Study of Adolescent to Adult Health. (Add health; N = 11,807). We calculated allostatic load scores based on respondent values ​​for 10 metabolic, cardiovascular, and inflammatory biomarkers measured at wave IV, when respondents were 24 to 34 years old. We then used negative binomial regression models to assess the combined effects of race / ethnicity, gender, and educational level on allostatic load, while controlling for key covariates. We found that black women had significantly higher allostatic load scores than white women and black men, net of education level and other covariates. Yet education has altered the relationship between race / ethnicity, gender, and allostatic load. Obtaining a college education was protective for white men and women, but no more and no less protective for other women and deleterious for black men. In other words, by the time they reach adulthood, the cumulative physiological burden of stress on black women and college-educated black men is already greater than among their similar or less educated white counterparts. . These findings provide important information about the intermediate physiological imbalance that underlies social inequalities in stress-related health outcomes, particularly those that occur at the intersections of race / ethnicity, gender, and educational attainment. They also suggest that research into his background should focus on previous periods of life.

PMID:34584929 | PMC:PMC8455854 | DO I:10.1016 / j.ssmph.2021.100771


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